The Shlezinger lab uses a multidisciplinary approach to address two broad questions: what are the mechanisms that enable fungi to overcome immune surveillance and cause infectious diseases and, conversely, how the host immune response can protect against fungal pathogens. The projects in the lab address common questions in pathogenesis and immunology at the molecular, cellular and whole-organism level. To decode these intricate interactions, we generate functional reporters of fungal physiology and apply cross-disciplinary techniques to monitor the outcome of individual fungal cell-host encounters within the complexities of an in vivo environment.
We are hiring new members
interested in all things fungi!
Human fungal pathogens account for an estimated1 billion infections and over 1.6 million deaths annually! Staggered by these numbers?
Come join our fungal
We study the pathobiology of eukaryotic pathogens using molecular tools that enable tracking of mammalian hosts-pathogen encounters at a single-cell resolution, combining cutting-edge technologies in immunology, microbiology and cell biology to address fundamental and translational questions related to fungal pathogenesis and host defenses.
Exciting projects focusing on host-induced cell death as a defense mechanism, fungal regulated cell death and novel approaches to anti-fungal therapy are waiting for you!